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Women's Health Weekly

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Breast Cancer



New findings reported from A.L. Pintocorreia and co-authors describe advances in breast cancer



September 18th, 2008

"We aimed to study the role of an insertion/deletion polymorphism in the Pepsinogen C (PGC) gene in the clinical outcome of 172 breast cancer patients," scientists in Oporto, Portugal report.

"The six polymorphic alleles were amplified using PCR. Our results indicate that patients carrying the allele 6 present a higher 5-year survival mean (83.4% of 6 allele carriers were alive at 5 years vs. only 68.6% of noncarriers, p = 0.001), suggesting a role for this polymorphism in the outcome of breast cancer patients," wrote A.L. Pintocorreia and colleagues.

The researchers concluded: "We hypothesize that PGC polymorphism can be a predictive biomarker in...


Source: Women's Health Weekly (2008-09-18)

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