Women's Health Weekly
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Breast Cancer
Recent studies from National Cancer Institute add new data to breast cancer
September 18th, 2008
According to recent research from the United States, "Individuals with mutations in breast cancer susceptibility genes BRCA1 and BRCA2 have up to an 80% risk of developing breast cancer by the age of 70. Sequencing-based genetic tests are now available to identify mutation carriers in an effort to reduce mortality through prevention and early diagnosis." "However, lack of a suitable functional assay hinders the risk assessment of more than 1,900 BRCA1 and BRCA2 variants in the Breast Cancer Information Core database that do not clearly disrupt the gene product. We have established a simple, versatile and reliable assay to test for the functional significance of...
Source: Women's Health Weekly (2008-09-18)
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