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Women's Health Weekly

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Breast Cancer



Researchers from Hamamatsu University, Medical Department detail findings in breast cancer



September 18th, 2008

According to recent research from Hamamatsu, Japan, "The possibility of interactions between natural products/supplements and conventional prescription medicines is one of the most important issues in pharmacotherapeutic safety. Recently, we reported that some terpenoids such as (R)-(+)-citronellal and glycyrrhetic acid, which are present in herbal medicines, can act as inhibitors of P-glycoprotein (MDR1/ABCB1)."

"In the present study, the effects of seven terpenoids on multidrug resistance-associated protein 2 (MRP2/ABCC2) and breast cancer resistance protein (BCRP/ABCG2)-mediated transport were investigated in vitro. Membrane vesicles were prepared from MRP2 cDNA...


Source: Women's Health Weekly (2008-09-18)

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