Women's Health Weekly
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Breast Cancer
Studies in the area of breast cancer reported from University of Palermo
September 18th, 2008
According to a study from Palermo, Italy, "It was reported that cadmium is able to exert a cytotoxic effect on tumor MDA-MB231 cells, which shows signs of ''non-classical'' apoptosis and is characterized by drastic changes in gene expression pattern." "In this study, we have extended our knowledge of metal-breast cancer cell interactions by analyzing some mitochondria-related aspects of the stress response to CdCl2 at either 5 or 50 mc M 24- or 96-h exposure, by cytochemical, conventional PCR and Northern/Western blot techniques. We demonstrated that (i) no modification of the mitochondrial mass was detectable due to CdCl2 exposure; (ii) the respiration activity...
Source: Women's Health Weekly (2008-09-18)
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