Women's Health Weekly
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Breast Cancer
Study results from F. Montemurro and colleagues in the area of breast cancer published
September 18th, 2008
"The vinka-alkaloyd vinorelbine is a potentially valuable treatment in patients with HER2-positive, trastuzumab-resistant advanced breast cancer. We sought to document the clinical activity of vinorelbine-based salvage treatments in this clinical setting," researchers in Turin, Italy report. "We analyzed a cohort of 424 consecutive women receiving trastuzumab-based therapy for HER2-positive advanced breast cancer. Of these, 299 were identified as progressing during the initial trastuzumab-based treatment, and 77 received vinorelbine-based therapy as first salvage treatment. Central review of pathological specimens revealed that 70 patients had HER2-amplification...
Source: Women's Health Weekly (2008-09-18)
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