Women's Health Weekly
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Breast Cancer
New breast cancer research from B. Gril et al outlined
September 25th, 2008
According to recent research published in the Journal of the National Cancer Institute, " The brain is increasingly being recognized as a sanctuary site for metastatic tumor cells in women with HER2-overexpressing breast cancer who receive trastuzumab therapy. There are no approved or widely accepted treatments for brain metastases other than steroids, cranial radiotherapy, and surgical resection." "We examined the efficacy of lapatinib, an inhibitor of the epidermal growth factor receptor (EGFR) and HER2 kinases, for preventing the outgrowth of breast cancer cells in the brain in a mouse xenograft model of brain metastasis. EGFR-overexpressing MDA-MB-231-BR...
Source: Women's Health Weekly (2008-09-25)
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