Women's Health Weekly
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Breast Cancer
New breast cancer study findings recently were reported by researchers at Churchill Hospital
September 25th, 2008
"The Auger electron-emitting radiopharmaceutical In-111-cliethylenetriaminepentaacetic acid human epidermal growth factor (In-111-DTPA-hEGF) binds the epidermal growth factor receptor (EGFR), is internalized, and translocates to the nucleus. The purpose of this study was to investigate the relationship between EGFR expression, DNA damage, and cytotoxicity in cells exposed to In-111-DTPA-hEGF," scientists in Oxford, the United Kingdom report. "Breast cancer cell lines with a range of EGFR expression levels were exposed to In-111-DTPA-hEGF or gamma-radiation. The cell lines (followed by number of EGFR per cell in parentheses) were MDA-MB-468 (1.3 x 10(6)), MDA-MB-231 (1.3...
Source: Women's Health Weekly (2008-09-25)
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