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Women's Health Weekly

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Wellcome Trust



Inflammatory response to infection and injury may worsen dementia



October 2nd, 2008

Inflammation in the brain resulting from infection or injury may accelerate the progress of dementia, research funded by the Wellcome Trust suggests. The findings, published this week in the journal Biological Psychiatry, may have implications for the treatment and care of those living with dementia.

Systemic inflammation – inflammation in the body as a whole – is already known to have direct effects on brain function. Episodes of delirium, in which elderly and demented patients become extremely disoriented and confused, are frequently caused by infections, injury or surgery in these patients. For example, urinary tract infections, which are typically bacterial, appear...


Source: Women's Health Weekly (2008-10-02)

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