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Women's Health Weekly

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Breast Cancer



Studies from Istanbul University provide new data on breast cancer



October 2nd, 2008

According to a study from Istanbul, Turkey, "It was aimed to review the literature and make a meta-analysis of the trials on both upfront, switching, and sequencing anastrozole in the adjuvant treatment of early breast cancer. The PubMed, ClinicalTrials.gov and Cochrane databases were systematically reviewed for randomized-controlled trials comparing anastrozole with tamoxifen in the adjuvant treatment of early breast cancer."

"The combined hazard rate of 4 trials for event-free survival (EFS) was 0.77 (95% CI: 0.70-0.85) (P < 0.0001) for patients treated with anastrozole compared with tamoxifen. In the second analysis in which only ITA, ABCSG 8, and ARNO 95 trials...


Source: Women's Health Weekly (2008-10-02)

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