Women's Health Weekly
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Breast Cancer
Studies from Stavanger University provide new data on breast cancer
October 2nd, 2008
According to a study from Stavanger, Norway, "Androgen receptor (AR) expression is prognostic for breast cancer. Techniques to determine AR levels include the dextran-coated charcoal method (charc-AR), which measures AR levels in both normal and cancer cells; immunohistochemical analysis (IHC-AR) of whole sections (WS), which targets cancer cells but relies on subjective assay interpretation; and IHC of tissue microarray (TMA) samples, an approach that can be inaccurate when AR heterogeneity is present." "This study compared charc-AR (n = 151). with quantitative IHC analysis (n = 138) of WS and TMA samples (1.7mm cylinder samples; 2.3 mm(2)). Charc-AR results correlated...
Source: Women's Health Weekly (2008-10-02)
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