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Serous Carcinoma

Research from University of Toronto provide new insights into serous carcinoma

Published in Women's Health Weekly, October 9th, 2008

"To update the data on the expression of 'mesothelioma markers' by serous carcinomas of various sites we have studied cases from ovary (n = 56), endometrium (n = 37), fallopian tube (n = 6), primary peritoneum (n = 5) and cervix (n = 3) using a panel of antibodies (WT1, P53, estrogen receptors, HER2/neu, D2-40, cytokeratin 5/6 and E-cadherin). Ovarian carcinomas demonstrated D2-40 and cytokeratin 5/6 immunoreactivity in 23.2 and 55.4% of cases, respectively," scientists in Toronto, Canada report.

"Endometrial carcinomas demonstrated D2-40 and cytokeratin 5/6 immunoreactivity in 43.2 and 37.8% of cases, respectively. D2-40 staining pattern was predominantly focal;...

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