Women's Health Weekly
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Breast Cancer
Reports from University of Lethbridge add new data to research in breast cancer
October 16th, 2008
"Many chemotherapy regiments are successfully used to treat breast cancer; however, often breast cancer cells develop drug resistance that usually leads to a relapse and worsening of prognosis. We have shown recently that epigenetic changes such as DNA methylation and histone modifications play an important role in breast cancer cell resistance to chemotherapeutic agents," investigators in Lethbridge, Canada report. "Another mechanism of gene expression control is mediated via the function of small regulatory RNA, particularly microRNA (miRNA); its role in cancer cell drug resistance still remains unexplored. In the present study, we investigated the role of miRNA in...
Source: Women's Health Weekly (2008-10-16)
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