Women's Health Weekly
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Breast Cancer
Reports summarize breast cancer study results from AstraZeneca
October 16th, 2008
According to a study from Macclesfield, the United Kingdom, "Fulvestrant is at least as effective as anostrozole in the treatment of postmenopausal women with advanced breast cancer whose disease has previously progressed or recurred on antiestrogen therapy. Pharmacokinetic data have shown that, at the approved dose (250 mg/month), it takes approximately 3-6 months for fulvestrant to reach steady-state levels." "Theoretically, a more rapid attainment of steady state might reduce the number of early progressions. A pharmacokinetic model simulating plasma concentrations expected to be achieved with a fulvestrant loading dose (LD) regimen suggested that steady state might...
Source: Women's Health Weekly (2008-10-16)
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