Women's Health Weekly
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Breast Cancer
Researchers at University of Sheffield have published new data on breast cancer
October 16th, 2008
" The potent antiresorptive drug zoledronic acid (Zol) enhances the antitumor effects of chemotherapy agents in vitro. We investigated the effects of clinically achievable doses of doxorubicin (Dox) and Zol, given alone, in sequence, and in combination, on the growth of established breast tumors in vivo," scientists in Sheffield, the United Kingdom report. " Female MF1 nude mice were inoculated subcutaneously with 5 x 105 human breast cancer MDA-MB-436 cells that stably expressed green fluorescent protein (ie, MDA-G8 cells). Beginning on day 7 after tumor cell injection, the mice were injected weekly for 6 weeks with saline, Dox (2 mg/kg body weight via intravenous...
Source: Women's Health Weekly (2008-10-16)
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