Women's Health Weekly
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Breast Cancer
Studies from Yale University add new findings in the area of breast cancer
October 16th, 2008
"Aromatase inhibitors (Al) inhibit peripheral conversion of androgens to estradiol and are commonly used as hormonal therapy for postmenopausal women with hormone receptor-positive breast cancer in the metastatic and adjuvant settings. Joint-related symptoms, however, are seen in a significant proportion of patients," investigators in the United States report. "Carpal tunnel syndrome (CTS) is a common nerve entrapment disorder affecting the median nerve. We describe 6 patients with newly diagnosed CTS after initiation of adjuvant Al therapy. Aromatase inhibitors were discontinued in several patients secondary to this toxicity with some switching to tamoxifen and most...
Source: Women's Health Weekly (2008-10-16)
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