Women's Health Weekly
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Cervical Cancer
Study findings on cervical cancer are outlined in reports from A. Chiarini and colleagues
October 16th, 2008
"Lamin B1, a major component of the nuclear lamina, anchors the nucleus to the cytoskeletal cage, and controls nuclear orientation, chromosome positioning and, alongside several enzymes, fundamental nuclear functions. Exposing polyomavirus-transformed rat pyF111 fibroblasts and human cervical carcinoma (HCC) C44 cells for 30 min to photoexcited perylenequinone calphostin C, i.e," investigators in Verona, Italy report. "Cal C-phi E, an established reactive oxygen species (ROS)generator and protein kinase C (PI(C) inhibitor, caused the cells to selectively oxidize and then totally destroy their nuclear lamin B1 by only 60 min after starting the treatment, i.e. when...
Source: Women's Health Weekly (2008-10-16)
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