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Women's Health Weekly

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Endometrial Cancer



Research results from V. Pandey and co-authors update knowledge of endometrial cancer



October 16th, 2008

According to recent research published in the journal Endocrinology, "Recent published data have demonstrated elevated levels of human GH (hGH) in endometriosis and endometrial adenocarcinoma. Herein, we demonstrate that autocrine production of hGH can enhance the in vitro and in vivo oncogenic potential of endometrial carcinoma cells."

"Forced expression of hGH in endometrial carcinoma cell lines RL95-2 and AN3 resulted in an increased total cell number through enhanced cell cycle progression and decreased apoptotic cell death. In addition, autocrine hGH expression in endometrial carcinoma cells promoted anchorage-independent growth and increased cell...


Source: Women's Health Weekly (2008-10-16)

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