Women's Health Weekly
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Breast Cancer
Reports outline breast cancer research from A. Eladdadi and colleagues
October 23rd, 2008
According to recent research from the United States, "We present a mathematical model to study the effects of HER2 over-expression on cell proliferation in breast cancer. The model illustrates the proliferative behavior of cells as a function of HER2 and EGFR receptors numbers, and the growth factor EGF." "This mathematical model comprises kinetic equations describing the cell surface binding of EGF growth factor to EGFR and HER2 receptors, coupled to a model for the dependence of cell proliferation rate on growth factor receptors binding. The simulation results from this model predict: (1) a growth advantage associated with excess HER2 receptors; (2) that...
Source: Women's Health Weekly (2008-10-23)
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