Women's Health Weekly
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Breast Cancer
Research conducted at College of Medicine has updated our knowledge about breast cancer
October 23rd, 2008
"ZBP1 (zipcode binding protein 1) is an RNA-binding protein involved in many posttranscriptional processes, such as RNA localization, RNA stability, and translational control. ZBP1 is abundantly expressed in embryonic development, but its expression is silenced in most adult tissues," scientists writing in the journal Molecular and Cellular Biology report. "Reactivation of the ZBP1 gene has been reported in various human tumors. In this study, we identified a detailed molecular mechanism of ZBP1 transactivation in breast cancer cells. We show that beta-catenin, a protein that functions in both cell adhesion and transcription, specifically binds to the ZBP1...
Source: Women's Health Weekly (2008-10-23)
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