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Women's Health Weekly

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Cervical Cancer



Researchers from University of Hong Kong describe findings in cervical cancer



October 23rd, 2008

"Uterine cervical cancer, the second most frequently occurring cancer in women worldwide, is tightly associated with the expression of high-risk human papillomavirus [mainly human papillomavirus (HPV)-16 and HPV18] oncogenes E6 and E7 and characteristically exhibits chromosomal instability. However, the mechanisms underlying chromosomal instability in cervical cancer are still not fully understood," investigators in Hong Kong, People's Republic of China report.

"In this study, we observed that two of three human cervical epithelial cell lines expressing HPV16 E6E7 became immortalized without extensive chromosomal instability and crisis. The introduction of transforming...


Source: Women's Health Weekly (2008-10-23)

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