Women's Health Weekly
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Chlamydia
Studies from G. Lenegrate and colleagues reveal new findings on chlamydia
October 23rd, 2008
According to recent research from the United States, "Chlamydia trachomatis is an obligate intracellular bacterial pathogen that causes various human diseases, including blindness caused by ocular infection and sexually transmitted diseases resulting from urogenital infection. After infecting host cells, Chlamydiae avoid alarming the host's immune system." "Among the immune evasion mechanisms, Chlamydiae can inhibit NF-kappa B activation, a crucial pathway for host inflammatory responses. In this study, we show that ChlaDub1, a deubiquitinating and deNeddylating protease from C. trachomatis, is expressed in infected cells. In transfection experiments, ChlaDub1...
Source: Women's Health Weekly (2008-10-23)
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