Women's Health Weekly
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Enzyme Research
Research from University of Cambridge provides new data on enzyme research
October 23rd, 2008
According to a study from Cambridge, the United Kingdom, "This study investigates involvement of beta-catenin signalling in regulation of p-glycoprotein (p-gp) expression in endothelial cells derived from brain vasculature. Pharmacological interventions that enhance or that block beta-catenin signalling were applied to primary rat brain endothelial cells and to immortalized human brain endothelial cells, hCMEC/D3, nuclear translocation of beta-catenin being determined by immunocytochemistry and by western blot analysis to confirm effectiveness of the manipulations." "Using the specific glycogen synthase kinase-3 (GSK-3) inhibitor 6-bromoindirubin-3'-oxime enhanced...
Source: Women's Health Weekly (2008-10-23)
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