Breast Cancer
Research from Harvard University, Division of Experimental Medicine has provided new information about breast cancer
Published in Women's Health Weekly, October 30th, 2008
Scientists discuss in 'Slit-2 induces a tumor-suppressive effect by regulating beta-catenin in breast cancer cells' new findings in breast cancer. "SLIT-2 is considered as a candidate tumor suppressor gene, because it is frequently inactivated in various cancers due to hypermethylation of its promoter region and allelic loss. However, the exact mechanism of its tumor-suppressive effect has not been elucidated," investigators in the United States report.
"Here, we observed that Slit-2-overexpressing breast cancer cells exhibited decreased proliferation and migration capabilities compared with control cells under in vitro conditions. These results were confirmed in vivo...
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