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Cancer Vaccines

Data on cancer vaccines described by researchers at Naval Medical Center

Published in Women's Health Weekly, October 30th, 2008

Investigators publish new data in the report 'Optimal dose and schedule of an HER-2/neu (E75) peptide vaccine to prevent breast cancer recurrence: from US Military Cancer Institute Clinical Trials Group Study I-01 and I-02.' "E75, a HER-2/neu-derived peptide, was administered as a preventive vaccine with granulocyte-macrophage-colony-stimulating factor (GM-CSF) in disease-free lymph node-positive (NP) and lymph node-negative (NN) breast cancer (BCa) patients. The optimal biologic dose (OBD) was determined based on toxicity and immunologic response," scientists in the United States report.

"Patients were vaccinated over 6 months (3, 4, or 6 times) with different doses of...

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