Women's Health Weekly
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Breast Cancer
New findings in breast cancer described by P. Kischel and co-researchers
October 30th, 2008
"Metastatic breast cancer cells are characterized by their high propensity to colonize the skeleton and form bone metastases, causing major morbidity and mortality. Identifying key proteins involved in the osteotropic phenotype would represent a major step toward the development of both new prognostic markers and new effective therapies," scientists in Liege, Belgium report. "Cell surface proteins differentially expressed in cancer cells are preferred potential targets for antibody-based targeted therapies. In this study, using cell surface biotinylation and a mass spectrometric approach, we have compared the profile of accessible cell surface proteins between the human...
Source: Women's Health Weekly (2008-10-30)
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