Women's Health Weekly
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Breast Cancer
Reports by H. Clar and co-researchers describe recent advances in breast cancer
October 30th, 2008
"Breast cancer is the most frequently diagnosed cancer among women in western countries and bone metastases of breast cancer cause significant morbidity. G proteins are important components of a multitude of transmembrane receptors and are involved in the regulation of intracellular signaling pathways such as parathormone receptors 1 and 2 (PTH1 and 2), extracellular calcium-sensing receptor, the calcitonin receptor and the OPG/RANKL-system," investigators in Austria report. "A common polymorphism in the gene encoding the G protein beta 3-subunit, GNB3 825C > T, has been linked to increased G protein activation. To analyse the role of this polymorphism in bone...
Source: Women's Health Weekly (2008-10-30)
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