Women's Health Weekly
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Breast Cancer
Research from University of Minnesota, Medical Department provide new insights into breast cancer
October 30th, 2008
"Breast cancer patients with brain metastasis have a dismal prognosis. We determined the ability of immunostimulatory CpG oligodeoxynucleotides (ODN) to treat or prevent brain metastasis in a mouse model," investigators in the United States report. "Mice bearing orthotopic breast carcinoma with or without concurrent i.e. tumors were treated by injections of CpG ODN at the primary tumor. Immunologic memory was tested by tumor rechallenge and immune responses were assessed by flow cytometry, delayed-type hypersensitivity, and CTL assays. Orthotopic tumors regressed in treated mice regardless of whether concurrent i.e. disease was present. In mice bearing only orthotopic...
Source: Women's Health Weekly (2008-10-30)
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