Women's Health Weekly
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Breast Cancer
Research results from K.L. Gorringe and co-authors update knowledge of breast cancer
October 30th, 2008
"Several studies in various populations have suggested that non-synonymous BARD1 variants are associated with increased breast cancer risk. Using DHPLC analysis we screened the coding region of BARD1 for variants in 210 probands of breast cancer families including 129 families with no mutations in BRCA1 or BRCA2," researchers in Melbourne, Australia report. "These families were ascertained in Australia through the Kathleen Cunningham Foundation Consortium for Research into Familial Breast Cancer (kConFab). Nine coding variants were detected among the kConFab families, including two novel variants (Thr598Ile and Ile692Thr). The frequency of five of these variants were...
Source: Women's Health Weekly (2008-10-30)
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