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GTx, Inc.

GTx Announces Investigational Ostarine MK-2866 Met the Primary Endpoint in the Phase II Cancer Cachexia Clinical Trial

Published in Women's Health Weekly, October 30th, 2008

GTx, Inc. (NASDAQ: GTXI) announced topline results of a Phase II clinical trial evaluating Ostarine(TM) (MK-2866), an investigational selective androgen receptor modulator (SARM), in patients with cancer induced muscle loss, also known as cancer cachexia. In this analysis, the study met its primary endpoint of absolute change in total lean body mass (muscle) compared to placebo and the secondary endpoint of muscle function (performance) after 16 weeks of treatment. GTx and Merck & Co., Inc. are collaborating to develop Ostarine and other SARMs, which are a new class of drugs with the potential to treat sarcopenia, which is the loss of skeletal muscle mass resulting in reduced physical...

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