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Breast Cancer

Studies from University of Colombo add new findings in the area of breast cancer

Published in Women's Health Weekly, October 30th, 2008

"Breast Cancer is the most commonly diagnosed cancer among Sri Lankan women. Germline mutations in the susceptibility genes BRCA1 and BRCA2 in hereditary breast/ovarian cancer, though low in prevalence, are highly penetrant and show geographical variations," scientists in Colombo, Sri Lanka report.

"There have been only a few reports from Asia on mutations in BRCA1/ 2 genes and none from Sri Lanka. A total of 130 patients with (N = 66) and without (N = 64) a family history of breast cancer, 70 unaffected individuals with a family history of breast cancer and 40 control subjects were analysed for BRCA1 mutations. All but exon 11 were screened by single strand...

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