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Women's Health Weekly

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Cancer



Study data from Emory University, Medical Department provide new insights into cancer



November 6th, 2008

"The nuclear factor-kappa B (NF-kappa B) signaling pathway has been targeted for therapeutic applications in a variety of human diseases, includuing cancer. Many naturally occurring substances, including curcumin, have been investigated for their actions on the NF-kappa B pathway because of their significant therapeutic potential and safety profile," researchers in the United States report.

"A synthetic mono-ketone compound termed 3,5-bis(2-flurobenzylidene) piperidin-4- one (EF24) was developed from curcumin and exhibited potent anticancer activity. Here, we report a mechanism by which EF24 potently suppresses the NF-kappa B signaling pathway through direct action on I...


Source: Women's Health Weekly (2008-11-06)

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