Women's Health Weekly
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Cancer Vaccines
Researchers from Yale University, Medical Department detail findings in cancer vaccines
November 6th, 2008
According to recent research published in the journal Clinical and Vaccine Immunology, "We are developing recombinant attenuated vesicular stomatitis virus (VSV) as a vaccine vector to generate humoral and cell-mediated immune responses. Here, we explore the use of VSV vaccines for cancer immunotherapy." "Immunotherapy targeting high-risk human papillomavirus (HPV) lesions has the potential to benefit HPV-infected individuals and cervical cancer patients by generating cytotoxic T cells that kill tumor cells that express viral antigens. A single dose of VSV expressing the HPV type 16 (HPV16) E7 oncogene was used for therapeutic vaccination of mice bearing TC-1...
Source: Women's Health Weekly (2008-11-06)
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