Women's Health Weekly
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Breast Cancer
Reports summarize breast cancer research from P.Z. Chen and co-authors
November 13th, 2008
According to recent research from Shanghai, People's Republic of China, "The PALB2 gene has an essential role in BRCA2-mediated DNA double-strand break repair and intra - S phase DNA damage checkpoint control, and its mutations are moderately associated with breast cancer susceptibility. This study was designed to investigate the common variants of PALB2 and their association with breast cancer risk." "Four single nucleotide polymorphisms (SNP; rs249954, rs249935, rs120963, and rs16940342) which tagged all 19 of the reported SNPs (minor allele frequency >0.05) covering PALB2 were selected and genotyped in 1,049 patients with breast cancer and 1,073 cancer-free...
Source: Women's Health Weekly (2008-11-13)
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