Women's Health Weekly
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Breast Cancer
Research reports on breast cancer from M.M. Caffarel and colleagues provide new insights
November 13th, 2008
"It has been recently shown that cannabinoids, the active components of marijuana and their derivatives, inhibit cell cycle progression of human breast cancer cells. Here we studied the mechanism of Delta(9)-tetrahydrocannabinol (THC) antiproliferative action in these cells, and show that it involves the modulation of JunD, a member of the AP-1 transcription factor family," researchers in Madrid, Spain report. "THC activates JunD both by upregulating gene expression and by translocating the protein to the nuclear compartment, and these events are accompanied by a decrease in cell proliferation. Of interest, neither JunD activation nor proliferation inhibition was...
Source: Women's Health Weekly (2008-11-13)
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