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Women's Health Weekly

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Breast Cancer



Scientists at National Cancer Institute report research in breast cancer



November 13th, 2008

"We investigated the influence of acute wounding on tumor growth in a syngeneic mouse breast cancer model. Metastatic mouse breast cancer cells (4T1) were orthotopically injected into the mammary fat pads of BALB/c mice, and animals were wounded locally by full thickness dermal incisions above the mammary fat pads or remotely above the scapula 9 days later," scientists writing in the journal Cancer Research report.

"Local, but not remote, wounding increased tumor size when compared with sham treatment. Injection of wound fluid close to the tumor site increased tumor growth, whereas in vitro wound fluid compared with serum increased the proliferation rate of 4T1...


Source: Women's Health Weekly (2008-11-13)

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