Women's Health Weekly
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Gene Therapy
Reports from University of Texas highlight recent research in gene therapy
November 13th, 2008
According to recent research from the United States, "Cytoglobin (CYGB) is a recently discovered vertebrate globin distantly related to myoglobin with unknown function. CYGB is assigned to chromosomal region 17q25, which is frequently lost in multiple malignancies." "Previous studies failed to detect evidence for mutations in the CYGB gene. Recent studies provided preliminary evidence for increased methylation of the gene in lung cancer. Our study was aimed at investigating the role of CYGB as a tumor suppressor gene. By nested methylation-specific DNA sequencing analysis of lung and breast cancer cell lines and bronchial and mammary epithelia] cell lines, we identified...
Source: Women's Health Weekly (2008-11-13)
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