Women's Health Weekly
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World Journal of Gastroenterology
Estrogen and progesterone receptor isoforms expression in the stomach of Mongolian gerbils
November 20th, 2008
We have previously shown that E2 and P4 have clear and distinct effects on inflammatory response and gastric epithelial changes during early H. pylori infection. Recently, Ohtani et al., have shown a protective role of E2 administration in H. pylori-infected InGas mice. Other studies have demonstrated that E2 and P4 have anti-ulcerative effects in murine gastric mucosa. ER and PR have been reported in human, mouse and rat stomach. However, there is no information to date of their expression and regulation in Mongolian gerbil stomach. Ovariectomized adult female gerbils were subcutaneously treated with E2, and E2+P4. Uteri and stomachs were removed, the latter were cut...
Source: Women's Health Weekly (2008-11-20)
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