Women's Health Weekly
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Breast Cancer
Investigators at Taipei Medical University release new data on breast cancer
November 20th, 2008
"Quercetin (QUE; 3,5,7,3 ',4 '-tetrahydroxyflavone) has been shown to possess several beneficial biological activities including antitumor, anti-inflammation and antioxidant properties; however, the effects of QUE in preventing invasion by breast carcinoma cells are still undefined. Increases in the protein, messenger RNA and enzyme activity levels of matrix metalloproteinase (MMP)-9 were observed in 12-O-tetradecanoylphorbol-13-acetate (TPA)-treated MCF-7 cells, and these were blocked by QUE, but not by quercitrin or rutin," scientists in Taipei, Taiwan report. "A translocation of protein kinase C (PKC)delta from the cytosol to the membrane followed by activation of...
Source: Women's Health Weekly (2008-11-20)
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