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Women's Health Weekly

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Breast Cancer



New findings from J.H. Yu and co-researchers in the area of breast cancer described



November 20th, 2008

In this recent report, researchers in Shenyang, People's Republic of China conducted a study "To investigate the apoptotic mechanism of pseudolaric acid B (PAB) in human breast cancer MCF-7 cells. 3-(4,5-Dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide analysis and morphological changes were, applied to detect apoptosis."

"The percentage of apoptotic and necrotic cells were calculated by the lactate dehydrogenase activity-based cytotoxicity assay, and the protein expression was examined by Western blot analysis. PAB and/or the mitogen-activated protein kinases, including p38, c-Jun-N-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK), did not...


Source: Women's Health Weekly (2008-11-20)

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