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Women's Health Weekly

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Columbia University's Mailman School of Public Health



First evidence that prenatal exposure to famine may lead to persistent epigenetic changes



November 20th, 2008

A study initiated by researchers at Columbia University Mailman School of Public Health and the Leiden University Medical Center in the Netherlands suggests that prenatal exposure to famine can lead to epigenetic changes that may affect a person's health into midlife. The findings show a trickle-down effect from pregnant women to the DNA of their unborn children and the timeframe over which such early damage can operate. While previous studies have suggested that adult disease risk may be associated with adverse environmental conditions early in development, these data are the first to show that early-life environmental conditions can cause epigenetic changes in humans that persist...


Source: Women's Health Weekly (2008-11-20)

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