Women's Health Weekly
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Breast Cancer
Research in the area of breast cancer reported from N. Bogdanova and colleagues
November 20th, 2008
"The NBS1/p95 protein has a pivotal role in the sensing and repair of chromosome breaks. A missense mutation in the NBS1 gene, I171V, has recently been associated with a ninefold increased risk of breast cancer in Polish patients," researchers in Hannover, Germany report. "Positive associations have also been reported for leukaemia and larynx cancer suggesting that I171V could be a more general susceptibility factor for malignancies. We investigated the prevalence of this mutation in two large hospital-based case-control series from Germany and from the Republic of Belarus. The I171V substitution was detected in 20/1,636 Byelorussian breast cancer patients and in...
Source: Women's Health Weekly (2008-11-20)
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