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Women's Health Weekly

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Breast Cancer



Research results from R.M.Z. Reena and co-authors update knowledge of breast cancer



November 20th, 2008

According to recent research from Malaysia, "This is a study aimed to examine the distribution pattern of a specific minichromosome maintenance protein 2 (MCM2) in benign and malignant breast tissue. We also aim to correlate the frequency of expression of MCM2 with the degree of tumor differentiation."

"We used immunohistochemistry to examine the distribution and expression pattern of MCM2 on formalin-fixed paraffin-embedded tissue sections of benign (n = 30) and malignant breast tissue (n = 70) (IDC 56, DCIS 4, ILC 2, nonductal 4, mixed type 4). We quantified MCM2 expression by calculating a labeling index, which represents the percentage of epithelial nuclei that...


Source: Women's Health Weekly (2008-11-20)

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