Human Papillomavirus

Research results from University of New Mexico update knowledge of human papillomavirus

Published in Women's Health Weekly, November 27th, 2008

"High-risk human papillomaviruses (HPVs) are small nonenveloped DNA viruses with a strict tropism for squamous epithelium. The viruses are causative agents of cervical cancer and some head and neck cancers, but their differentiation-dependent life cycles have made them difficult to study in simple cell culture," researchers in the United States report.

"Thus, many aspects of early HPV infection remain mysterious. We recently showed the high-risk HPV type 31 (HPV31) enters its natural host cell type via caveola-dependent endocytosis, a distinct mechanism from that of the closely related HPV16 (Smith et al., J. Virol. 81: 9922-9931, 2007). Here, we determined the...

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Source: Women's Health Weekly (2008-11-27)

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