Diabetes
Recent findings in diabetes described by researchers from Kobe University, Medical Department
Published in Women's Health Weekly, November 27th, 2008
"A missense mutation in the low density lipoprotein receptor-related protein 6 gene (LRP6) was recently shown to be responsible for a disorder characterized by early-onset coronary artery disease as well as diabetes mellitus (DM), hyperlipidemia, hypertension, and osteoporosis. Mice deficient in LRP5, a closely related paralog of LRP6, manifest a marked impairment in glucose tolerance," scientists writing in the Endocrine Journal report.
"The aim of the present study was to examine whether common variants of LRP5 and LRP6 are associated with Type 2 DM or dyslipidemia in Japanese individuals. Thirteen single nucleotide polymorphisms (SNPs) of LRP6 and nine SNPs of...
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