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Women's Health Weekly

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Breast Cancer



New breast cancer research reported from Yale University, Medical Department



November 27th, 2008

"Transforming growth factor-beta (TGF-beta)-mediated signals play complicated roles in the development and progression of breast tumour. The purposes of this study were to analyse the genotype of TGF-beta 1 at T29C and TGF-beta 1 phenotype in breast tumours, and to evaluate their associations with IGFs and clinical characteristics of breast cancer," researchers in the United States report.

"Fresh tumour samples were collected from 348 breast cancer patients. TGF-beta 1 genotype and phenotype were analysed with TaqMan (R) and ELISA, respectively. Members of the IGF family in tumour tissue were measured with ELISA. Cox proportional hazards regression analysis was...


Source: Women's Health Weekly (2008-11-27)

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