Women's Health Weekly
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Breast Cancer
Reports from Medical University of South Carolina highlight recent research in breast cancer
November 27th, 2008
According to a study from the United States, "Prostate derived ETS factor (PDEF) is an ETS (epithelial-specific E26 transforming sequence) family member that has been identified as a potential tumor suppressor. In multiple invasive breast cancer cells, PDEF expression inhibits cell migration by preventing the acquisition of directional morphological polarity conferred by changes in cytoskeleton organization." "In this study, microarray analysis was used to identify > 200 human genes that displayed a common differential expression pattern in three invasive breast cancer cell lines after expression of exogenous PDEF protein. Gene ontology associations and data mining...
Source: Women's Health Weekly (2008-11-27)
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