Women's Health Weekly
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Breast Cancer
Research from L.C. Walker and co-researchers yields new findings on breast cancer
November 27th, 2008
According to a study from Brisbane, Australia, "Germline mutations in BRCA1 or BRCA2 confer an increased lifetime risk of developing breast or ovarian cancer, but variable penetrance suggests that cancer susceptibility is influenced in part by modifier genes. Microarray expression profiling was conducted for 69 irradiated lymphoblastoid cell lines derived from healthy controls, or from cancer-affected women with a strong family history of breast and ovarian cancer carrying pathogenic mutations in BRCA1 or BRCA2, or with no BRCA1/2 mutations (BRCAX)." "Genes discriminating between BRCA1, BRCA2 or BRCAX and controls were stratified based on irradiation response and/or...
Source: Women's Health Weekly (2008-11-27)
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