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Breast Cancer Prevention

Reports outline breast cancer prevention study findings from Ludwig-Maximilians University

Published in Women's Health Weekly, December 4th, 2008

Research findings, 'Lineage infidelity and expression of melanocytic markers in human breast cancer,' are discussed in a new report. "In previous analyses, dual expression of melanocytic and epithelial molecular markers have been described as indicators of lineage infidelity for breast cancer cells that lose their epithelial identity. Here we demonstrated that this is a much more frequent phenomenon in human breast carcinomas, usually affecting only a part of the tumor," scientists in Munich, Germany report.

"Accordingly we detected, in 18 out of 100 breast carcinomas, immunohistochemically focally positive cells for the melanocytic marker Melan A. The presence and...

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