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Women's Health Weekly

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Breast Cancer



New data from Environmental Protection Agency illuminate research in applied pharmacology



December 4th, 2008

"Juvenile Fats have been reported to be more sensitive to the acute neurotoxic effects of the pyrethroid deltamethrin than adults. While toxicokinetic differences between juveniles and adults are documented, toxicodynamic differences have not been examined," researchers in the United States report.

"Voltage-gated sodium channels, the primary targets of pyrethroids, are comprised of alpha and beta subunits, each of which have multiple isoforms that are expressed in a developmentally-regulated manner. To begin to test whether toxicodynamic differences Could contribute to age-dependent deltamethrin toxicity, deltamethrin effects were examined on sodium currents in Xenopus...


Source: Women's Health Weekly (2008-12-04)

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