Women's Health Weekly
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Cancer
Researchers from Vrije University Amsterdam detail findings in cancer
December 4th, 2008
"Array comparative genomic hybridization (array CGH) is widely used for studying chromosomal copy number aberrations (CNAs) on a genome-wide and high-resolution scale in heritable disorders and cancers. The aim of this study was to test if the separate channels of dual channel arrays can be interchanged (across array) to either make array CGH more sensitive and cost effective and/or to generate profiles of CNAs and copy number variations (CNVs)," scientists in Netherlands report. "Therefore the BT474 breast cancer cell line was compared with a mix of normal reference DNAs hybridized on different arrays and days and DNA copy number profiles were evaluated. Quality was...
Source: Women's Health Weekly (2008-12-04)
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